How reliable is your HbA1c test? Revisiting the use of HbA1c in cystic fibrosis-related diabetes (CFRD) screening

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The use of fructosamine in cystic fibrosis-related diabetes (CFRD) screening.

OBJECTIVE To determine whether serum fructosamine correlates with glycemic control and clinical outcomes in patients being screened for cystic fibrosis-related diabetes (CFRD). METHODS Fructosamine and percent predicted forced expiratory volume in 1s (FEV1) were measured in patients undergoing a 2h oral glucose tolerance test (OGTT) for CFRD screening. Fractional serum fructosamine (FSF) was ...

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Cystic Fibrosis-Related Diabetes: Screening and Diagnosis

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Use of HbA1c in the diagnosis of diabetes.

The WHO was very clear that an HbA(1c) of 48 mmol/mol (6.5%) and above is diagnostic of diabetes. They were less clear regarding results that fell below 48 mmol/mol. The WHO recognize that individuals with HbA(1c) values below the cut-off point may still have diabetes, but give no guidance on how to investigate further. It is important that these individuals, who may be at increased risk of dev...

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2019

ISSN: 1569-1993

DOI: 10.1016/j.jcf.2019.02.001